Nowadays novel sensing technologies are needed for biosensing and medicine. There is a considerable effort directed towards the development of novel label-free and sensitive approaches for biosensors. Among numerous optical sensors, plasmonic nanosensors are of great promise due to their spectral tunability and good adaptability to modern nanobiotechnologies. Localized surface plasmon resonance (LSPR) is the oscillation of the conducting electrons on metal surface, and it is very sensitive to the variation of environmental refractive index. The LSPR is considered as a useful sensing parameter that provides very good biological information. The SPR absorbtion peak also can be adjusted by changing the nano structure. The BME ETT Nanotechnology Laboratory developed a novel LSPR sensor transducer production method. During my work I used MATLAB software with MNPBEM toolbox to simulate different nanoparticles (sphere and rod) and real nanoparticle structures. The purpose of this simulation was to find the nano structure with the best sensitivity.